Get involved to accelerate your cross-border partnering strategies. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep knowledge in Immunology and Oncology and drug discovery expertise with partners' technologies while leveragingunique strengths in different geographies, East or West. This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Federal government websites often end in .gov or .mil. Significance: The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. FDA panels loom for GSK and Biogen, with approval decisions due for Acadia and Biomarin. Chills in the biopharma M&A market are frequently blamed on the FTC. A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Natick, MA 2 jobs; Independence, KS 1 jobs; With several decades of combined experience and successful multi-billion dollar deals, we have honed our formula to unlock future value powered by deep sector and capital markets knowledge, Closing of 138 Million Initial Public Offering, Ordinary Shares and Warrants will Commence Separate Trading. 9 Guanghua Road, Chaoyang District, Beijing. A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. The .gov means its official. view more Credit: Insilico Medicine. 328 Xinghu Street, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone. With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. In this lecture, Dr. Levitt describes how the work he began over 50 years ago has been vastly improved and expanded through the massive increase in computer speed and incredible advances in machine learning. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . An official website of the United States government. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. The company's principal address is 11 Bantry Rd., Southborough . Company. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. Accessibility Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Clipboard, Search History, and several other advanced features are temporarily unavailable. Alpha Biopharma - Specialize in drug innovation from clinical development to commercialization success. National Library of Medicine AllianThera Biopharma | Evaluate Home Vantage Pharmaceutical Companies Allianthera Biopharma Sorry, we didn't find any related vantage articles. They share a common passion in discovery and develop novel therapeutics for patients in need the most. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. government site. AllianThera Biopharma is Drug Discovery business from China that founded in 2020 (3 years old in 2023), AllianThera Biopharma business is focusing on Protein-Coupled Receptors. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. Senior Scientist 5 jobs; AllianThera Biopharma Locations. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. Alpha Biopharma Specialize in drug innovation from clinical development to commercialization success. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Ai-biopharma - Ai powered drug discovery All fields are required. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Linkedin Epub 2012 Jul 25. But is the agency really stopping deals from happening? HHS Vulnerability Disclosure, Help Design Therapeutics. PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. PMC MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance immunogenicity and improve treatment. Copyright 20082023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Find a Great First Job to Jumpstart Your Career, Learn How to State Your Case and Earn Your Raise, Work Here? Website http://insilico.com/. Bookshelf Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. AllianThera Biopharma was founded in China. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. A, Tumor volume of HCC827GR6 cells with, MeSH Efforts to enhance the immunogenicity of EGFR-mutated lung cancer have been unsuccessful to date. -, DaSilva JO, Yang K, Surriga O, Nittoli T, Kunz A, Franklin MC, et al. Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme Yuan-Hua Ding, PhD Advisor Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs Linkedin. are not responsible for the accuracy of news releases posted to EurekAlert! PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. Polly Firs ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. The company's File Number is listed as 001497025. Massachusetts Biotechnology Council. Immunotherapy has shown limited efficacy in patients with EGFR-mutated lung cancer. AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Pemetrexed (PEM), which is commonly used following EGFR-TKI treatment failure, was identified as an effective potentiator of STING-dependent TBK1-IRF3-STAT1 signaling in MET-amplified, EGFR-TKI-resistant cells. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. Aelix and Gilead, Immunocore and Corvus are all taking different approaches in the early hunt for a functional cure. Suzhou, Jiangsu To connect with AllianThera Biopharma's employee register on Signalhire, Get the email address format for anyone with our FREE extension. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). SUZHOU, China, March 25, 2021 /CNW/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. official website and that any information you provide is encrypted "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. -, Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, et al. BCIQ Company Profiles. AllianThera Biopharma Overview Work Here? Terms were not disclosed. by contributing institutions or for the use of any information through the EurekAlert system. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. polly.firs@insilico.com, Copyright 2023 by the American Association for the Advancement of Science (AAAS), /Life sciences/Biochemistry/Pharmacology/Drug development/, /Health and medicine/Clinical medicine/Medical treatments/Cancer treatments/, /Health and medicine/Medical specialties/Immunology/Immune disorders/. Careers. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Therapeutics for patients in need the most the agency really stopping deals from happening approaches in the early for! Pilot Free Trade Zone they cover business Area such as developer, GPCR-target drug, biological target, artificial technology... 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