CipherBio data reveals that the US is an undisputed leader in life science space as the location attracting most of the Biotech funding since the beginning of 2019 69% of all deals closed in the top 10 locations globally accounts for the US (Figure 2). Business Products and Services (B2B), Consumer Products and Services (B2C), Financial Services, Information Technology, Materials and Resources. In addition to its private-equity investing, RA Capital has brought companies public through SPACs with mixed results. Six top firms held more than $1 billion in equity: Arch Venture Partners, Novo Holdings, Flagship Pioneering, RA Capital Management, Perceptive Advisors, and SoftBank. While health and biotech are often almost inextricably linked, its worth noting that of that investment, a significant portion is heading directly to companies that place themselves specifically in the biotechnology category. , which conducts research and development of pharmaceuticals related to COVID-19. Here is a breakdown of some of those leaders, based on Crunchbase data. Boston-based. It is owned entirely by the Novo Nordisk Foundation, the holdings limited of the Novo Group. Private biotech investing is a small piece of what Fidelity does. The German pharma giant Bayer's VC arm has made high-profile investments in health companies, three of which went public in 2021: Century Therapeutics, Pyxis Oncology, and Recursion Pharmaceuticals. The center of it all is biotechnology, with over 430 biotech companies. RA Capital Management and OrbiMed led the way in both total dollars invested and the number of venture capital funding rounds led in the biotech industry last yearthe only two firms to make it onto both lists. Largest investment: 18.2 million shares of Adagio Therapeutics worth $46.9 million at the time of its IPO, Total holding value of 2021 IPOs: $468.7 million. It is focused on investment opportunities in high-potential companies. ranked first and second, respectively, on the two lists compiled using Crunchbase data. Founded in 1999, Chevron Technology Ventures is the corporate venture capital arm of Chevron and is based in Houston, Texas. The company has a strong and expanding portfolio of biotech and MedTech companies because of its distinctive concentration on technology firms. The firm seeks to make minority investments in seed-stage, early-stage, and later-stage companies. The firm seeks to invest in seed-stage, early-stage and later-stage companies. Bridge, Convertible Debt, Early Stage VC, Seed Round. In 1999, Versant Ventures, Inc., a Menlo Park, California-based venture capital company, was founded. Crunchbase Daily. Many investors contributed their efforts in early-stage Biotech to find the next Moderna. 10 Figure calculated based on adding the value of the new $450 million fund with the $3.5 billion previously disclosed by the firm. Largest investment: 44 million shares of Sana Biotechnology worth $1.1 billion at the time of its IPO, Total holding value of 2021 IPOs: $1.9 billion. WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! 1 We also found that biotech CEO: John Doerr (chairman), Brook Byers (founder). 16 Best Oklahoma Based Venture Capital Firms of 2021. by Tenner Smith 2 years ago. But two of those investment firms have emerged as major leaders, not only in the number of biotech funding rounds led, but also in overall dollars invested into the industry. Early Stage VC, Later Stage VC, Seed Round. However, the situation has tremendously changed since the market crash began in November 2021. Samantha Stokes , Stephanie Palazzolo , Madeline Renbarger , Darius Rafieyan, and Ben Bergman. Leander, Texas 78641 Since Although the two firms emerged as leaders in the data, they still make up a small part of the more than $120 billion in venture capital funds globally that poured into health and biotech startups as of Dec. 1 this year, Crunchbase data shows. Leading a funding round is a big undertaking. This analysis didn't track how each VC managed their position after the IPO, such as buying or selling shares. The firm seeks investments in seed-stage, early-stage and later-stage companies. The year 2021 is closing with a biotech investment rush as Eir Ventures, Apollo Health Ventures, and Mercks venture capital arm M Ventures raise impressive funds to speed up life sciences innovation. The firm primarily prefers to invest in the information technology sectors. Current biopharma portfolio companies: Achaogen, Alcresta, Allena Pharmaceuticals, Amicus Therapeutics, Anaptys, Attercor, Cadence Pharmaceuticals, Founded in 2005, S3 Ventures is a venture capital firm based in Austin, Texas. Since then, the company has raised seven more funds, totaling over $2.5 billion, making it one of the worlds largest and most renowned Biosciences venture capital companies. Year established: Established 1993 as Schroder Ventures Life Sciences. Alex Philippidis Senior News Editor Genetic Engineering & Biotechnology News. See: http://www.sec.gov/Archives/edgar/data/1611731/000161173114000001/xslFormDX01/primary_doc.xml. US biotechs still led on investments, although Europe Insider analyzed corporate filings to identify the venture-capital firms that shaped these biotechs and are positioned to build on their success in 2022. The capital total is a staggering 46% increase from its last set of funds, closed in May 2021 at $1.3 billion. Largest investment: 37.5 million shares of Instil Bio worth $751 million at the time of its IPO, Total holding value of 2021 IPOs: $750.6 million. 3. Flagship, based in Cambridge, Massachusetts, is more of a venture-creation firm than a traditional VC it often creates the companies it invests in. VC investment in the biopharma space is likely to surpass $20 billion in 2021, driven by the need to fund trials and build out research and development programs, as clinical trials resume and elective procedures restart. 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Essex Woodlands Health Ventures, City (cities) where offices are located: Palo Alto, CA; Houston; New York; London; Shanghai, Fund size and status: More than $2.5 billion under management across eight funds (4), Current fund: $900 million Fund VIII, closed 2009 (4), Current biopharma portfolio companies: Acura Pharmaceuticals, Biotoscana, Bioventus, Catalyst Biosciences, Chroma Therapeutics, Corium, Curis, Echo Therapeutics, Elusys Therapeutics, Horizon Pharma, IntegenX, LightSciences Oncology, Medicinova, Molecular Partners, Open Monoclonal Technology, Oraya Therapeutics, Revance Therapeutics, Symphogen, Ziopharm Oncology, City (cities) where offices are located: Cambridge, MA; New York; Palo Alto, CA, Fund size and status: $2.6 billion under management across seven funds, Current funds: $450 million Venrock VII, closed July 2014 and intended to invest in technology and healthcare companies; $350 million Venrock VI, closed 2010 (5), Current biopharma portfolio companies: Acceleron Pharma, Achaogen, Anacor Pharmaceuticals, Ariosa Diagnostics, Avalanche Biotech, AVEO Pharmaceuticals, Celladon, Cerulean, Constellation Pharmaceuticals, CymaBay Therapeutics, Fate Therapeutics, Hua Medicine, Infinity Pharmaceuticals, Intarcia Therapeutics, Ironwood Pharma, Juno Therapeutics, QuatRx Pharmaceuticals, Receptos, Vitae Pharmaceuticals, City (cities) where offices are located: Boston (6); South San Francisco, CA; Gainesville, FL; Munich, Fund size and status: More than $2.6 billion committed capital under management across five funds, Current fund: Approximately $300 million MPM BioVentures V L.P., closed 2010 (7), Current biopharma portfolio companies: 23andMe, Amphivena Therapeutics, Anthera Pharmaceuticals, Aratana Therapeutics, Astute Medical, Celladon, Cerecor, Chiasma, Conatus Pharmaceuticals, Epizyme, Iconic Therapeutics, Mitokyne, Proteon Therapeutics, Radius Health, Rhythm Pharmaceuticals, SAI, Selexys Pharmaceuticals, Sideris Pharmaceuticals, Solasia Pharma, Syndax Pharmaceuticals, Theraclone Sciences, True North Therapeutics, Vascular Pharmaceuticals, Verastem, City (cities) where offices are located: Princeton, NJ, and San Diego, Fund size and status: More than $2.7 billion under management across eight funds, Current fund: $500 million Domain Partners VIII, closed 2009, Current biopharma portfolio companies: Achaogen, Achillion Pharmaceuticals, Adynxx, Afferent Pharmaceuticals, Aldeyra Therapeutics, Alimera Sciences, Applied Proteomics, Ariosa Diagnostics, Ascenta Therapeutics, Asmacure, Astute Medical, Atara Biotherapeutics, aTyr Pharma, BioNano Genomics, Cantex Pharmaceuticals, Celator Pharmaceuticals, Clovis Oncology, CoDa Therapeutics, CoLucid Pharmaceuticals, Dicerna Pharmaceuticals, Domain Elite Holdings, Domain Russia Investments, Eddingpharm International Holdings, Epic Sciences, Esperion Therapeutics, Evoke Pharma, Five Prime Therapeutics, IntegenX, Marinus Pharmaceuticals, Meritage Pharma, NovaDigm Therapeutics, Ocera Therapeutics, Oraya Therapeutics, Orexigen Therapeutics, Otonomy, ProteinSimple, Regardo Biosciences, Sera Prognostics, Syndax Pharmaceuticals, Tobira Therapeutics, Tragara Pharmaceuticals, VentiRx Pharmaceuticals, Veracyte, Zogenix, Fund size and status: $2.8 billion under management across 10 funds, Current fund: $650 million InterWest Partners X, closed 2008, Current biopharma portfolio companies: Applied Genetic Technologies (AGTC), Alvine Pharmaceuticals, Arcion Therapeutics, Carbylan Therapeutics, Cebix, Centrexion, Cidara Therapeutics, Drais Pharmaceuticals, Eiger BioPharmaceuticals, Lycera, MacroGenics, Ocera Therapeutics, On Demand Therapeutics, Paratek Pharmaceuticals, PMV Pharma, QuatRx Pharmaceuticals, RadioRx, Tesaro, Trius Therapeutics, USDS, Xenon Pharmaceuticals, City (cities) where offices are located: Cambridge, MA. The Legal 500; United States . The firm seeks to invest in firms operating in the information technology and healthcare sectors. Largest investment: 16.2 million shares of Theseus Pharmaceuticals worth $259 million at the time of its IPO, Total holding value of 2021 IPOs: $988.4 million. The Legal 500; Europe, Middle East & Africa . The Series D funding was led by Lightspeed Venture Partners and existing investors Greenoaks Capital Partners and Index Ventures. They will explore which venture capital funds performed best during the pandemic, and of course be taking your questions live. Blackstone, one of the largest private venture capital firms, founded Blackstone Life Sciences in 2018 after acquiring Clarus Ventures, an equity firm with $2.6 billion in assets. , however, participated in Adagios Series A, B and C rounds. This years list shows the upward progression of VC firms; the lowest-ranked of this years firms had $1.25 billion under management, compared with more than $1.1 billion for the Top 30 Venture Capital Firms of 2013. These VC firms led the most funding rounds for biotech startups this year between Jan. 1 and Dec. 1, according to Crunchbase data. Morgenthaler VenturesLife Sciences Team, City (cities) where offices are located: Palo Alto, CA; Boston; Boulder, CO, Fund size and status: More than $2.5 billion under management, Current fund: $400 million Fund IX, closed 2008 and used in part for investment in life-sciences companies. No money was reported to have been raised, and a size was not disclosed for the fund. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! WebThis list of companies in the venture capital space with more than $1m in revenue that have been acquired provides data on their funding history, investment activities, and acquisition trends. New Leaf Venture Partners (NLVP) invested in Biopharmaceuticals during its growth and venture phases. Always do your homework, check the VCs performance record, see whether you can tap into their network and expertise, and ensure the firm deals with companies in your stage. WebThe 45 most important VCs in Texas, according to other VCs. On the other hand, the number of special purpose acquisition companies (SPACs), which raise funds through an initial public offering (IPO) to acquire another company within two years, is expected to dwindle in 2021 compared to 2020, PitchBook said. Founded in 2012, Saudi Aramco Energy Ventures is the corporate venture capital arm of Aramco Oil Company. Following is a list of the top 15 venture capital firms in 2023. The investments we included were those disclosed in company S-1 filings, and the value of the holdings was based on the companies' initial pricing at the time of their IPOs. Healthtech and biotech has consistently been a top sector for the destination of venture capital in recent years. Kleiner Perkins Caufield & Byers (KPCB), City (cities) where offices are located: Menlo Park, CA; San Francisco; Beijing; Shanghai, Fund size and status: More than $7 billion in assets under management across 19 funds (13), Current fund: $525 million KPCB XV, closed 2012 (13), Current biopharma portfolio companies:(14) ApniCure, Armo BioSciences, Atara Bio, Auxogyn, Crescendo Bioscience, Elcelyx, Epizyme, FivePrime Therapeutics, Focal, Foundation Medicine, Oculeve, Onyx Pharmaceuticals, Orexigen, Pacific Biosciences, Pharmacopeia, Pharmacyclics, Practice Fusion, Rapid Micro Biosystems, Tesaro, True North Therapeutics. In addition to the returns from its portfolio companies that went public in 2021, Arch has $1.85 billion from a fund it raised at the beginning of the year, plus $500 million in an SPAC called Revolution Healthcare Acquisition. Venture capital. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Biotech companies are valued at $2T, a 4.1x increase since 2017. WebFive out of the ten businesses selected to present at the 2021 event went on to raise $50m - $150m each within 12 months of the event and one raising a $23m Series A (others planning to raise in the next 6 months). Angermayer, who is also a movie producer, is especially interested in trying to develop psychedelics into medicines, with investments in ATAI Life Sciences and Compass Pathways, both of which focus on mental health. Added to this, a new administration in the United States and its policy proposals, taxes, immigration, trade policy, and other issues that directly affect both VC investors and companies will all be on the table next year, PitchBook said in its 2021 U.S. venture capital outlook report. Fund size and status: More than $14 billion in committed capital across 14 funds, Current fund: $2.6 billion New Enterprise Associates 14 L.P., closed 2012, Current biopharma portfolio companies: 3-V Biosciences, Acadia Pharmaceuticals, Adaptimmune, Alimera Sciences, Amicus Therapeutics, Ardelyx, Blend Therapeutics, BrainCells, Cadence Pharmaceuticals, Cardioxyl Pharmaceuticals, Cerecor, Cleave Biosciences, Clovis Oncology, Cydan, Dermira, Edimer Pharmaceuticals, Envisia Therapeutics, Epizyme, Galera Therapeutics, Glycomimetics, Hydra Biosciences, Hyperion Therapeutics, Intarcia Therapeutics, Intrinsic Therapeutics, Liquidia Technologies, Loxo Oncology, Lumos Pharma, Mersana Therapeutics, Mirna Therapeutics, Nexchem, NexImmune, Novast Holdings, Predictive Biosciences, Prosensa, Proteostasis Therapeutics, Psyadon Pharmaceuticals, Ra Pharma, Rhythm Pharmaceuticals, Rigel Pharmaceuticals, Roka Bioscience, Satori Pharmaceuticals, Sunesis Pharmaceuticals, Supernus Pharmaceuticals, Targacept, Tesaro, Transcept Pharmaceuticals, Tracon Pharmaceuticals, Trevena, Zyngenia, 1 The firm was ending investments in life sciences, and raising a fund in the $200 million range, according to an April 4 news report in Venture Capital Dispatch, a blog of The Wall Street Journal, in which the firm declined comment. 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